Retinoid and related drugs

Drug Safety Update

January 2026: Isotretinoin – changes to prescribing guidance and additional risk minimisation measures

October 2025: Isotretinoin – updates to prescribing guidance and survey of services

October 2023: Isotretinoin (Roaccutane▼): introduction of new safety measures, including additional oversight of the initiation of treatment for patients under 18 years of age

 June 2019: Oral retinoid medicines▼: revised and simplified pregnancy prevention educational materials for healthcare professionals and women

 March 2019: Medicines with teratogenic potential: what is effective contraception and how often is pregnancy testing needed?

 December 2014: Isotretinoin: risk of serious skin reactions.

 December 2014: Oral retinoids: pregnancy prevention—reminder of measures to minimise teratogenic risk

Oral isotretinoin (Roaccutane®) is a toxic and teratogenic drug and can only be prescribed by Consultant Dermatologists.

  • On Formulary Preferred
  • On Formulary Second Line
  • On Formulary Third Line
  • Specialist Initiation
  • Secondary Care Only
  • Not Approved for Formulary