Angioedema
National Guidance
Hereditary angioedema - acute treatment: https://www.england.nhs.uk/commissioning/wp-content/uploads/sites/12/2013/09/b09-p-b.pdf
Hereditary angioedema - prophylactic treatment: https://www.england.nhs.uk/wp-content/uploads/2018/07/Plasma-derived-C1-esterase-inhibitor-for-prophylactic-treatment-of-hereditary-angioesema-types-I-and-II.pdf
NICE Guidance
TA1101 Garadacimab for preventing recurrent attacks of hereditary angioedema in people 12 years and over, October 2025 - via tertiary services only.
These drugs should be used by appropriate specialists in accordance with national and local guidance.
For prophylaxis of known HAE patients with C1- esterase inhibitor, including pre-planned surgery – supply to come from tertiary centre.
For HAE treatment of acute attacks of angioedema with icatibant or C1-esterase inhibitor (follow guidance) – to use patients own supply (from tertiary centre) where possible. If this is not available the local Trust can supply – please inform the local pharmacy HCD team on the next working day so that NHSE funding can be claimed.
For non-HAE treatment of acute attacks of angioedema – local Trust can supply (Trust-funded).
| Pack |
|---|
| 1 vial |
| Pack |
|---|
| 1 vial |
| Pack |
|---|
| 1 vial |
| Pack |
|---|
| 1 vial |
| Pack |
|---|
| 1 pre-filled disposable injection |
| 3 pre-filled disposable injection |
- On Formulary Preferred
- On Formulary Second Line
- On Formulary Third Line
- Specialist Initiation
- Secondary Care Only
- Not Approved for Formulary