Migraine

Drug Safety Update

June 2023: Non-steroidal anti-inflammatory drugs (NSAIDs): potential risks following prolonged use after 20 weeks of pregnancy

 January 2017: Intravenous N-acetylcysteine (NAC) for paracetamol overdose: reminder of authorised dose regimen; possible need for continued treatment with NAC. 

 December 2014: Treating paracetamol overdose with intravenous acetylcysteine: new guidance

NICE Guidance (see also drug specific links below)

CG150 Headaches in over 12s: diagnosis and management

 TA260 Botulinium toxin type A for the prevention of headaches in adults with chronic migraine, June 2012

Other drugs used in the treatment of migraine particularly prophylaxis against an attack include propranolol, topiramate, gabapentin and botulinum toxin.

See here for K&M ICB Management of Adults with Headaches and Migraines in Primary Care

Note: Migraine services in East Kent are currently provided by Bethesda Medical Centre, NOT East Kent Hospitals University NHS Foundation Trust

Pack
100 tablet
100 tablet (10 x 10 tablets)
1000 tablet
16 tablet (2 x 8 tablets)
30 tablet (3 x 10 tablets)
32 tablet
Pack
100 capsule (10 x 10 capsules)
16 capsule
32 capsule
Pack
100 tablet (10 x 10 tablets)
24 tablet (4 x 6 tablets)
60 tablet
Pack
100 ml
500 ml
Pack
100 ml
1000 ml
200 ml
Pack
100 ml
500 ml
Pack
100 ml
1000 ml
200 ml
500 ml
Pack
10 suppository
Pack
10 suppository
Pack
10 suppository (2 x 5 suppositories)
Pack
10 suppository (2 x 5 suppositories)
Pack
10 vial
Pack
32 tablet (4 x 8 tablets)
100 tablet
Pack
10 suppository
Pack
10 suppository
Pack
24 tablet
48 tablet (4 x 12 tablets)
84 tablet
Pack
24 tablet
48 tablet (4 x 12 tablets)
84 tablet (7 x 12 tablets)
Pack
100 ml
150 ml
500 ml
Pack
60 tablet
28 tablet
84 tablet
Pack
28 tablet
Pack
3 tablet
6 tablet
Pack
12 tablet
2 tablet
3 tablet
6 tablet
Pack
3 tablet
6 tablet
Pack
12 tablet
2 tablet
4 tablet
6 tablet
Pack
12 tablet
2 tablet
4 tablet
6 tablet
Pack
2 unit dose
Pack
2 pre-filled disposable injection

In accordance with NICE TA919

See here for K&M Rimegepant Prescribing Guideline for Primary Care

Pack
2 tablet
8 tablet

In accordance with NICE TA919

See here for K&M Rimegepant Prescribing Guideline for Primary Care

Pack
2 tablet
8 tablet

Reduce dose to 10 mg once daily with concurrent use of potent CYP3A4 inhibitors, OATP inhibitors, or telmisartan.

Pack
28 tablet
Pack
28 tablet

Migraine prophylaxis - specialist neurologist prescribing only

Pack
1 capsule
  • On Formulary Preferred
  • On Formulary Second Line
  • On Formulary Third Line
  • Specialist Initiation
  • Secondary Care Only
  • Not Approved for Formulary