Antidepressants - Serotonin Re-uptake Inhibitors

Drug Safety Update

January 2021: SSRI/SNRI antidepressant medicines: small increased risk of postpartum haemorrhage when used in the month before delivery

 December 2011: Citalopram and escitalopram QT interval prolongation new maximum daily dose recommendations.

 March 2010: Fluoxetine: possible small risk of congenital cardiac defects

NICE guidance

 CG31: Obsessive compulsive disorder, November 2005

NG222: Depression in adults recognition and management, updated April 2018

CG113: Generalised anxiety disorder and panic disorder in adults: management

Kent and Medway NHS and Social Care Partnership (KMPT) Formulary has detailed information for the treatment of depression follow the link below (this includes information for primary care prescribers)

 Depression

Guidelines on the the diagnosis and treatment of depression have been published this includes advice on the choice of antidepressant

Pack
28 tablet
Pack
28 tablet
30 tablet
Pack
28 tablet

Note: 8mg (4 drops) is therapeutically equivalent to a 10mg tablet

Pack
15 ml

Please do NOT prescribe 25mg, 150mg & 200mg tablets.

Prescribe 50mg & 100mg tablets ONLY.

Pack
28 tablet
30 tablet
Pack
14 tablet
28 tablet
30 tablet

Paroxetine is a second-line agent included in the Kent and Medway NHS Social Care Partnership formulary. Consider alternative antidepressants before initiating

Pack
28 tablet
Pack
14 tablet
28 tablet
30 tablet
Pack
30 tablet
  • On Formulary Preferred
  • On Formulary Second Line
  • On Formulary Third Line
  • Specialist Initiation
  • Secondary Care Only
  • Not Approved for Formulary