All Antimicrobial's should be prescribed according to Trust antimicrobial policy or on the advice of a microbiologist. Restricted antimicrobials should be prescribed for the use or department specified unless on advice of the microbiologist. Please note some non formulary items maybe prescribed on strict advice of the microbiology team direction only.
Where antimicrobials are listed in the NICE/PHE Summary of antimicrobial prescribing guidance and this guidance is agreed locally, that those antibiotics are considered on formulary when prescribed in line with the guidance
Drug Safety Update
May 2014: Voriconazole: reminder of risk of liver toxicity, phototoxicity and squamous cell carcinoma.
July 2018: Parenteral amphotericin B: reminder of risk of potentially fatal adverse reaction if formulations confused
July 2020: Liposomal and lipid-complex formulations: name change to reduce medication errors
Never interchange liposomal, pegylated-liposomal, lipid-complex, and conventional formulations that contain the same drug substance
October 2020: Flucytosine (Ancotil): new contraindication in patients with DPD deficiency
Triazole antifungals (e.g. fluconazole, itraconazole, voriconazole) have the potential to interact with a wide variety of drugs please check BNF for details
