Tuberculosis
All Antimicrobial's should be prescribed according to Trust antimicrobial policy or on the advice of a microbiologist. Restricted antimicrobials should be prescribed for the use or department specified unless on advice of the microbiologist. Please note some non formulary items maybe prescribed on strict advice of the microbiology team direction only.
Where antimicrobials are listed in the NICE/PHE Summary of antimicrobial prescribing guidance and this guidance is agreed locally, that those antibiotics are considered on formulary when prescribed in line with the guidance
NICE guidance
NG33: Tuberculosis
Rifampicin is a key component of any antituberculosis regimen. It may also be used for serious staphylococcal infections, e.g. endocarditis and also as first line in the prophylaxis for meningitis contacts. Rifampicin is an enzyme inducer and has numerous drug interactions including the contraceptive pill (see BNF and SPC).
Pyridoxine should be given with isoniazid for the prophylaxis of isoniazid-induced neuropathy.
Rifampicin is an antibiotic used to treat specific infections. Always follow the relevant antimicrobial prescribing guidance (Trust or Primary Care).
- Tuberculosis – Hospital-only use. Rifampicin for the treatment of tuberculosis should be initiated and managed under specialist supervision in secondary care.
- Other indications – May be prescribed in primary care where indicated (e.g. prevention of secondary cases of meningococcal meningitis, staphylococcal infections), in line with local guidelines or microbiologist advice.
| Pack |
|---|
| 100 capsule |
| Pack |
|---|
| 60 capsule |
| Pack |
|---|
| 120 ml |
| Pack |
|---|
| 1 vial |
| Pack |
|---|
| 84 tablet (4 x 21 tablets) |
| Pack |
|---|
| 56 tablet (4 x 14 tablets) |
| Pack |
|---|
| 100 tablet (5 x 20 tablets) |
| Pack |
|---|
| 28 tablet |
| Pack |
|---|
| 1 ml |
| 500 ml |
| Pack |
|---|
| 10 ampoule |
| Pack |
|---|
| 30 tablet (3 x 10 tablets) |
| Pack |
|---|
| 1 ml |
For use under microbiology/TB specialist advice only
| Pack |
|---|
| 10 vial |
| 1 vial |
For use under microbiology/TB specialist advice only
| Pack |
|---|
| 100 capsule |
| 1 capsule |
- On Formulary Preferred
- On Formulary Second Line
- On Formulary Third Line
- Specialist Initiation
- Secondary Care Only
- Not Approved for Formulary