Other Antibacterials

Fusidic acid is incompletely absorbed and doses recommended for the suspension are proportionately higher than those for sodium fusidate tablets.

For primary care: It is strongly recommended that GPs discuss management of all cases of C. difficile with microbiology to ensure appropriate management. Guidance on prescribing can be found here- 'Accessing treatment for Clostridioides difficile Infection (CDI) in Primary Care'

For secondary care: To be used under Consultant Microbiologist advice only. A Blu-teq form must be completed by the initiating hospital doctor.

Rifampicin is an antibiotic used to treat specific infections. Always follow the relevant antimicrobial prescribing guidance (Trust or Primary Care).

• Tuberculosis – Hospital-only use. Rifampicin for the treatment of tuberculosis should be initiated and managed under specialist supervision in secondary care.
• Other indications – May be prescribed in primary care where indicated (e.g. prevention of secondary cases of meningococcal meningitis, staphylococcal infections), in line with local guidelines or microbiologist advice

Linezolid should be initiated in a hospital environment on the advice of a consultant microbiologist only.

Chloramphenicol may cause blood disorders and use is restricted to life threatening infections on the advice of a consultant microbiologist.

See BNF for monitoring requirements.

This is reserved for complicated skin and soft tissue infections and right sided endocarditis caused by resistant Gram-positive bacteria particularly MRSA. It is available for use on the advice of a consultant microbiologist only.

Not for MTW.

Caftaroline should be initiated in a hospital environment on the advice of a consultant microbiologist only.