Aminoglycosides
All Antimicrobial's should be prescribed according to Trust antimicrobial policy or on the advice of a microbiologist. Restricted antimicrobials should be prescribed for the use or department specified unless on advice of the microbiologist. Please note some non formulary items maybe prescribed on strict advice of the microbiology team direction only.
Where antimicrobials are listed in the NICE/PHE Summary of antimicrobial prescribing guidance and this guidance is agreed locally, that those antibiotics are considered on formulary when prescribed in line with the guidance
Drug Safety Update
January 2021: Aminoglycosides (gentamicin, amikacin, tobramycin, and neomycin): increased risk of deafness in patients with mitochondrial mutations
NICE Guidance
TA 276 Colistimethate sodium and tobramycin dry powders for inhalation for treating pseudomonas lung infection in cystic fibrosis. March 2013
Colistin, gentamicin and tobramycin nebs are also approved for adult patients with bronchiectasis (non-CF) in line with BTS guidelines. For specialist respiratory initiation under microbiology recommendation only. Colistin is the 1st line choice.
Restricted antibiotic - must be recommended or approved for use by a consultant microbiologist.
| Pack |
|---|
| 5 vial |
Caution when switching brands as they are not equivalent in excipient content and bronchospasm may occur.
| Pack |
|---|
| 5 vial |
| Pack |
|---|
| 56 ampoule ((14 x 4) x 4ml ampoules) |
- On Formulary Preferred
- On Formulary Second Line
- On Formulary Third Line
- Specialist Initiation
- Secondary Care Only
- Not Approved for Formulary