Urinary frequency, enuresis and incontinence

Drug Safety Update

 October 2015: Mirabegron (Betmiga▼): risk of severe hypertension and associated cerebrovascular and cardiac events

 December 2014: Botulinum toxin products: rare but serious risks

NICE Guidance (also see drug-specific links below)

 CG97: Lower urinary tract symptoms in men: management, June 2015

NG123: Urinary incontinence and pelvic organ prolapse in women: management, updated June 2019

CG148: Urinary incontinence in neurological disease: assessment and management,

TA290: Mirabegron for treating symptoms of overactive bladder, June 2013

Local Guidance

See here for local primary care guidance on the management of OAB in women

Vibegron can be prescribed second line in accordance with NICE TA999 for treating the symptoms of overactive bladder syndrome. The Kent and Medway pathway of care will be updated in due course.

Pack
30 tablet (3 x 10 tablets)
Pack
30 tablet (3 x 10 tablets)
Pack
56 tablet (4 x 14 tablets)
Pack
56 tablet (4 x 14 tablets)
Pack
28 capsule (2 x 14 capsules)

Not for use in the frail/elderly patient

Pack
56 tablet (8 x 7 tablets)
84 tablet (12 x 7 tablets)
Pack
56 tablet
Pack
56 tablet (8 x 7 tablets)
Pack
30 tablet
Pack
30 tablet
Pack
8 patch
Pack
150 ml
Pack
150 ml
Pack
90 tablet
60 tablet
100 tablet

Caution: Due to unit differences in the potency assay, unit doses for different brands of Botulinum A toxin are NOT interchangeable.

Pack
1 vial
2 vial
6 vial
Pack
1 vial
2 vial
  • On Formulary Preferred
  • On Formulary Second Line
  • On Formulary Third Line
  • Specialist Initiation
  • Secondary Care Only
  • Not Approved for Formulary