Corticosteroids (Gastroenterology)
Drug Safety Update
August 2017: Corticosteroids: rare risk of central serous chorioretinopathy with local as well as systemic administration. Local administration includes inhaled, intranasal, epidural, intraarticular, topical dermal and periocular routes. Advise patients to report any blurred vision or other visual disturbances.
NICE Guidance
NG129: Crohn’s disease: management, May 2019
NG130: Ulcerative colitis: management, May 2019
Prescribing Notes
Budesonide rectal foam enemas are the preferred, most cost-effective rectal option
Budesonide CR is less effective than conventional corticosteroids but may have fewer side effects.
Budesonide CR or Beclometasone Dipropionate MR (Clipper®) have been agreed for use as “specialist initiation”. They must only be initiated using the locally agreed prescribing pathways which have been developed with specialist guidance.
In K&M it has also been agreed that it can be prescribed for the maintenace of EoE in adults and induction and maintenance of EoE in children, under the direction of a gastroenterologist.
| Pack |
|---|
| 100 tablet |
| 1000 tablet |
| 28 tablet |
| 500 tablet |
| Pack |
|---|
| 100 tablet |
| 28 tablet |
| 30 tablet |
| 500 tablet |
The TEVA brand should be dispensed for children who cannot swallow tablets
| Pack |
|---|
| 100 tablet |
| 1000 tablet |
| 28 tablet |
| 30 tablet |
| Pack |
|---|
| 30 tablet |
| Pack |
|---|
| 30 tablet (3 x 10 tablets) |
| Pack |
|---|
| 1 vial |
NICE Guidance
Budesonide orodispersible tablet for inducing remission of eosinophilic oesophagitis
| Pack |
|---|
| 100 capsule |
| Pack |
|---|
| 100 capsule |
| Pack |
|---|
| 60 sachet |
Budesonide (Jorveza) orodispersible tablets can be initiated by a gastroenterologist for the induction of remission of eosinophilic oesophagitis (EoE) in adults in accordance with NICE TA 708. Click TA for more information.
In K&M it has also been agreed that it can be prescribed for the maintenance of EoE in adults and induction and maintenance of EoE in children (off-licence), under the direction of a gastroenterologist.
| Pack |
|---|
| 90 tablet (9 x 10 tablets) |
Dose recommended: Therapy cycles of no more than four weeks are recommended.
| Pack |
|---|
| 30 tablet |
- On Formulary Preferred
- On Formulary Second Line
- On Formulary Third Line
- Specialist Initiation
- Secondary Care Only
- Not Approved for Formulary