Macular oedema

Drug Safety Update

 January 2022: Brolucizumab (Beovu▼): risk of intraocular inflammation and retinal vascular occlusion increased with short dosing intervals

 July 2020: Systemically administered VEGF pathway inhibitors: risk of aneurysm and artery dissection

 August 2017: Corticosteroids: rare risk of central serous chorioretinopathy with local as well as systemic administration

 April 2016: Aflibercept (Zaltrap▼): minimising the risk of osteonecrosis of the jaw

NICE Guidance (see also drug specific links below)

 NG82: Age-related macular degeneration, January 2018.

 NG1022: Bevacizumab gamma for treating wet age-related macular degeneration, December 2024.

These drugs are for specialist use only and should be used in accordance with NICE guidance.

Triamcinolone acetonide preservative-free (Intracinol) is approved for vitreous visualisation during intraocular surgery and unlicensed (off label) use where necessary in macular oedema and non-infectious ocular inflammation.

  • On Formulary Preferred
  • On Formulary Second Line
  • On Formulary Third Line
  • Specialist Initiation
  • Secondary Care Only
  • Not Approved for Formulary