Macular degeneration

Drug Safety Update

January 2022: Brolucizumab (Beovu▼): risk of intraocular inflammation and retinal vascular occlusion increased with short dosing intervals

July 2020: Systemically administered VEGF pathway inhibitors: risk of aneurysm and artery dissection

 April 2016: Aflibercept (Zaltrap▼): minimising the risk of osteonecrosis of the jaw

NICE Guidance (see also drug specific links below)

 NG82: Age-related macular degeneration, January 2018.

NG1022: Bevacizumab gamma for treating wet age-related macular degeneration, December 2024.

These drugs are for specialist use only and should be used in accordance with NICE guidance.

  • On Formulary Preferred
  • On Formulary Second Line
  • On Formulary Third Line
  • Specialist Initiation
  • Secondary Care Only
  • Not Approved for Formulary