Progestogens

Drug Safety Update

 September 2019: Hormone replacement therapy (HRT): further information on the known increased risk of breast cancer with HRT and its persistence after stopping

 December 2014: Hormone Replacement Therapy - updated advice before prescribing HRT healthcare professionals should carefully consider the potential benefit and risks for every woman

Local guidance

See here for K&M HRT Prescribing Guideline

NICE Guidance

NG23: Menopause: identification and management

Please note that not all of the progestogen preparations listed below are licensed or on formulary for the following indications:
- Progestogenic opposition of oestrogen HRT
- Prevention of endometrial hyperplasia during oestrogen replacement therapy
Please see the above K&M HRT Prescribing Guideline for progestogen-only HRT preparations which are on formulary for managing menopausal symptoms

Pack
30 tablet (3 x 10 tablets)
Pack
10 tablet
100 tablet (10 x 10 tablets)
Pack
10 tablet
100 tablet (10 x 10 tablets)
90 tablet (6 x 15 tablets)
Pack
100 tablet
60 tablet

Generic micronised progesterone 100mg capsules are first-line over the brand Utrogestan, as this is more cost efficient and in line with national guidance on prescribing medication generically.

Pack
30 capsule (2 x 15 capsules)
  • On Formulary Preferred
  • On Formulary Second Line
  • On Formulary Third Line
  • Specialist Initiation
  • Secondary Care Only
  • Not Approved for Formulary