Angiotensin-converting enzyme inhibitors (ACE Inhibitors)

Drug Safety Update

Drug Safety Update June 2026: Be aware of the distinction between bradykinin- and histamine-mediated angioedema, as treatment strategies differ significantly 

Drug Safety Update April 2020: Coronavirus (COVID-19): latest guidance on medicines safety - antihypertensives

 February 2016: Co-prescribing an ACE inhibitor or Angiotensin-II receptor antagonists with potassium sparing diuretics - risk of fatal hyperkalaemia 

  June 2014: Safety concerns when combining medicines from different classes of renin-angiotensin system blocking agents - this combination is not recommended.

  May 2009: ACE inhibitors and Angiotensin-II receptor antagonists should not be used by breast feeding mothers in the first few weeks after delivery.

  Dec 2007: ACE inhibitors and Angiotensin-II receptor antagonists should not be used at any stage during pregnancy